Description

4-Bromo-6-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its complex halogenated structure makes it a valuable scaffold for constructing novel compounds with targeted biological and material properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the creation of new pesticides, herbicides, and fungicides, leveraging its halogenated quinoline core for bioactivity.
• Material Science Precursor: Serves as a starting material for synthesizing organic ligands, dyes, and photoactive compounds used in electronic and optical materials.
• Chemical Synthesis Scaffold: Employed in medicinal and combinatorial chemistry for structure-activity relationship (SAR) studies and library synthesis due to its modifiable functional groups.
• Academic & Industrial R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new chemical reactions and catalytic processes.

Basic Information

Product Name	4-Bromo-6-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-23-6
Molecular Formula	C₁₄H₁₃BrClNO₂
Molecular Weight	342.62 g/mol
Synonyms	Ethyl 4-Bromo-6-Chloro-8-Methylquinoline-3-Carboxylate; 8-Methyl-4-bromo-6-chloroquinoline-3-carboxylic Acid Ethyl Ester; 4-Bromo-6-chloro-8-methyl-3-quinolinecarboxylic Acid Ethyl Ester; 1242260-23-6; Quinoline-3-carboxylic acid, 4-bromo-6-chloro-8-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.