Description

4-Bromo-8-Chloro-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its complex halogenated and esterified structure, which provides versatile reactivity for constructing sophisticated molecular architectures. This compound is essential for research chemists and process developers in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated quinoline core for bioactivity.
• Material Science Precursor: Serves as a starting material for creating functionalized organic ligands used in catalysis and advanced polymeric materials.
• Chemical Synthesis Scaffold: Utilized in medicinal and combinatorial chemistry for structure-activity relationship (SAR) studies and library synthesis due to its multiple reactive sites.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new chemical transformations involving halogenated heterocycles.

Basic Information

Product Name	4-Bromo-8-Chloro-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-22-5
Molecular Formula	C₁₄H₁₃BrClNO₂
Molecular Weight	342.62 g/mol
Synonyms	Ethyl 4-Bromo-8-Chloro-6-Methylquinoline-3-Carboxylate; 4-Bromo-8-Chloro-6-Methyl-3-Quinolinecarboxylic Acid Ethyl Ester; 8-Chloro-4-Bromo-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester; 4-Bromo-8-Chloro-6-Methyl-quinoline-3-carboxylic Acid Ethyl Ester; 1242260-22-5; Ethyl 4-Bromo-8-chloro-6-methyl-3-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-8-Chloro-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.