Description

4-Amino-6-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable quinoline derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily targeted at research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based drug candidates, particularly for antimalarial, antibacterial, and anticancer research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that leverage the quinoline scaffold.
• Material Science Research: Serves as a building block for creating organic ligands, dyes, and photoactive materials due to its functionalized aromatic structure.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and constructing complex heterocyclic compounds.
• Fine Chemical Production: An intermediate in the multi-step synthesis of specialty chemicals requiring a specific, functionalized quinoline core.

Basic Information

Product Name	4-Amino-6-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-21-4
Molecular Formula	C₁₃H₁₃ClN₂O₂
Molecular Weight	264.71 g/mol
Synonyms	Ethyl 4-Amino-6-chloro-8-methylquinoline-3-carboxylate; 4-Amino-6-chloro-8-methylquinoline-3-carboxylic acid ethyl ester; 6-Chloro-8-methyl-4-aminoquinoline-3-carboxylic acid ethyl ester; AQCE; 1242260-21-4; Quinoline-3-carboxylic acid, 4-amino-6-chloro-8-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Amino-6-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.