Description

4-Bromo-7-Fluoroquinoline-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering precise bromo and fluoro substitution points for targeted molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its halogenated quinoline core for bioactivity.
• Material Science Building Block: Serves as a starting material for creating organic semiconductors, fluorescent dyes, and photoactive compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for method development and discovery chemistry in university and CRO laboratories.
• Custom Synthesis: Provides a versatile scaffold for contract manufacturing organizations (CMOs) to produce bespoke compounds for client projects.

Basic Information

Product Name	4-Bromo-7-Fluoroquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-18-9
Molecular Formula	C₁₂H₉BrFNO₂
Molecular Weight	298.11 g/mol
Synonyms	Ethyl 4-Bromo-7-fluoroquinoline-3-carboxylate; 4-Bromo-7-fluoroquinoline-3-carboxylic acid ethyl ester; 7-Fluoro-4-bromoquinoline-3-carboxylic acid ethyl ester; 1242260-18-9; 4-Bromo-7-fluoro-3-quinolinecarboxylic acid ethyl ester; Ethyl 7-fluoro-4-bromoquinoline-3-carboxylate; 3-Quinolinecarboxylic acid, 4-bromo-7-fluoro-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Bromo-7-Fluoroquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.