Description

4-Amino-5-Chloro-8-Methoxyquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This quinoline derivative is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents. The compound is supplied to meet the stringent quality demands of modern chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, particularly for therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development and production of new-generation pesticides and herbicides, leveraging its bioactive quinoline core.
• Chemical Synthesis Building Block: Serves as a versatile starting material for organic chemists in academia and industry for constructing more complex molecules.
• Material Science Research: Investigated for potential applications in creating functional organic materials and ligands for catalytic systems.

Basic Information

Product Name	4-Amino-5-Chloro-8-Methoxyquinoline-3-Carboxylic Acid
CAS No.	1242260-17-8
Molecular Formula	C₁₁H₉ClN₂O₃
Molecular Weight	252.66 g/mol
Synonyms	5-Chloro-8-methoxy-4-aminoquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 4-amino-5-chloro-8-methoxy-; 4-Amino-5-chloro-8-methoxyquinoline-3-carboxylic acid; 1242260-17-8; ACMC-209p5t; AKOS040759216; ZINC000003870786; SCHEMBL21806427
EINECS	Contact for details

Quality Control

Our production of 4-Amino-5-Chloro-8-Methoxyquinoline-3-Carboxylic Acid adheres to a strict quality management system to ensure batch-to-batch consistency and high purity. The material is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.