Description

4-Bromoquinoline-3-Carboxylic Acid Ethyl Ester is a high-value brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it a versatile building block for constructing complex heterocyclic frameworks, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways where the quinoline scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Material Science: Building block for creating organic semiconductors, light-emitting diodes (OLEDs), and other functional organic materials due to its electron-deficient quinoline core.
• Chemical Synthesis: Serves as a versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization to create diverse chemical libraries.
• Academic & Contract Research: Essential reagent for methodological studies and the discovery of new chemical reactions in university and CRO laboratories.

Basic Information

Product Name	4-Bromoquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-12-3
Molecular Formula	C₁₂H₁₀BrNO₂
Molecular Weight	280.12 g/mol
Synonyms	Ethyl 4-Bromoquinoline-3-carboxylate; 4-Bromo-3-quinolinecarboxylic Acid Ethyl Ester; 4-Bromoquinoline-3-carboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 4-bromo-, ethyl ester; Ethyl 4-bromoquinoline-3-carboxylate; 4-Bromoquinoline-3-carboxylate ethyl ester; 4-Bromo-3-ethoxycarbonylquinoline
EINECS	Contact for details

Quality Control

Our 4-Bromoquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for advanced intermediates used in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.