Description

4-Amino-7,8-Difluoroquinoline-3-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant commercial and research interest. Its core value lies in its unique molecular scaffold, which is critical for the synthesis of advanced pharmaceutical intermediates and active pharmaceutical ingredients (APIs). This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel quinolone-based therapeutics and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• API Synthesis: Serves as a critical building block for constructing complex Active Pharmaceutical Ingredients (APIs) with enhanced biological activity.
• Agrochemical Research: Used in the development of new agrochemicals, such as herbicides and pesticides, leveraging its difluoroquinoline core.
• Chemical Biology Probes: Employed in medicinal chemistry and drug discovery programs to create molecular probes for studying biological pathways.
• Material Science: Potential use as a monomer or precursor for synthesizing specialty polymers and advanced organic materials.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process scale-up projects.

Basic Information

Product Name	4-Amino-7,8-Difluoroquinoline-3-Carboxylic Acid
CAS No.	1242260-11-2
Molecular Formula	C10H6F2N2O2
Molecular Weight	224.17 g/mol
Synonyms	4-Amino-7,8-difluoroquinoline-3-carboxylic acid; 7,8-Difluoro-4-aminoquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 4-amino-7,8-difluoro-; 4-Amino-7,8-difluoro-3-quinolinecarboxylic acid; ADFQCA; 1242260-11-2; Difluoroquinoline carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 4-Amino-7,8-Difluoroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.