Description

4-Amino-5,8-Dichloroquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its functionalized quinoline core. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, potentially for antimicrobial, anticancer, or anti-inflammatory applications.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or pesticides with specific activity profiles.
• Chemical Synthesis: Used in organic synthesis for constructing complex molecular architectures, leveraging its reactive amino and ester functional groups.
• Material Science Research: Investigated as a monomer or precursor for creating specialty polymers or organic electronic materials with unique properties.
• Dye & Pigment Industry: Potential intermediate for synthesizing specialized quinoline-derived dyes and colorants.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and methodological studies in universities and contract research organizations.

Basic Information

Product Name	4-Amino-5,8-Dichloroquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-10-1
Molecular Formula	C₁₂H₁₀Cl₂N₂O₂
Molecular Weight	285.13 g/mol
Synonyms	Ethyl 4-Amino-5,8-dichloroquinoline-3-carboxylate; 5,8-Dichloro-4-aminoquinoline-3-carboxylic acid ethyl ester; 4-Amino-5,8-dichloro-3-quinolinecarboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4-amino-5,8-dichloro-, ethyl ester; ADAQE; ADQCE; 1242260-10-1 (CAS).
EINECS	Contact for details

Quality Control

Our 4-Amino-5,8-Dichloroquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.