Description

4-Bromo-5,7-Dimethylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, functionalized quinoline derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile brominated and esterified scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinoline core's bioactivity.
• Material Science Precursor: Serves as a starting material for creating functionalized organic ligands and complexing agents used in catalysis and electronic materials.
• Chemical Synthesis: The bromine atom offers a versatile handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Heck), while the ester group allows for hydrolysis or transesterification.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-5,7-Dimethylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-06-5
Molecular Formula	C₁₄H₁₄BrNO₂
Molecular Weight	308.17 g/mol
Synonyms	Ethyl 4-Bromo-5,7-dimethylquinoline-3-carboxylate; 4-Bromo-5,7-dimethyl-3-quinolinecarboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4-bromo-5,7-dimethyl-, ethyl ester; 1242260-06-5; 4-Bromo-5,7-dimethylquinoline-3-carboxylic acid ethyl ester; Ethyl 4-bromo-5,7-dimethylquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Bromo-5,7-Dimethylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.