Description

Bromo[[1,3-Bis[(4S,5S)-1-Benzoyl-4,5-Diphenyl-2-Imidazolin-2-Yl]Benzene]Palladium(II)] is a highly specialized, chiral palladium complex designed for advanced catalytic applications. This compound matters for its role in facilitating highly selective and efficient cross-coupling reactions, which are critical for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel organic materials.

Application

• Asymmetric Catalysis: Employed as a chiral catalyst in enantioselective cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations, for the synthesis of chiral biaryl compounds.
• Pharmaceutical Intermediate Synthesis: Critical for constructing complex, stereochemically defined intermediates in the development of new therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Fine Chemical Production: Used in the production of high-value specialty chemicals, agrochemicals, and advanced materials where precise stereochemical control is required.
• Methodology Development: A valuable tool for academic and industrial research groups developing new catalytic methodologies for C-C and C-N bond formation.
• Ligand-Precursor Complex: Serves as a pre-formed, air-stable source of a chiral palladium-ligand system, simplifying catalyst handling and ensuring reproducible performance in sensitive reactions.

Basic Information

Product Name	Bromo[[1,3-Bis[(4S,5S)-1-Benzoyl-4,5-Diphenyl-2-Imidazolin-2-Yl]Benzene]Palladium(II)]
CAS No.	1242081-29-3
Molecular Formula	C58H44BrN4O2Pd
Molecular Weight	1016.71 g/mol
Synonyms	Bromo[1,3-bis[(4S,5S)-1-benzoyl-4,5-diphenyl-4,5-dihydro-1H-imidazol-2-yl]benzene]palladium; (S,S)-Bromo-Pd-BIPI Complex; Palladium(II) Bromide Complex with Chiral Bis(imidazoline) Ligand; Chiral Palladacycle; Bromo(1,3-bis[(4S,5S)-1-benzoyl-4,5-diphenyl-2-imidazolin-2-yl]benzene)palladium; CAS 1242081-29-3
EINECS	Contact for details

Quality Control

Our Bromo[[1,3-Bis[(4S,5S)-1-Benzoyl-4,5-Diphenyl-2-Imidazolin-2-Yl]Benzene]Palladium(II)] is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, essential for reproducible catalytic performance. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and residual metal content. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term stability, storage under an inert atmosphere (argon or nitrogen) is recommended to prevent potential decomposition.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Palladium Content	10.0 - 11.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.