Description

3-(Fluoromethyl)Piperidine Hcl is a high-purity, fluorinated piperidine derivative, a crucial building block in modern pharmaceutical and agrochemical research. Its value lies in its unique structure, which incorporates a reactive fluoromethyl group onto the piperidine scaffold, enabling the synthesis of novel bioactive compounds. This intermediate is essential for medicinal chemists and process development scientists working in drug discovery, particularly for the development of central nervous system (CNS) agents and other therapeutic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological and psychiatric disorders.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme mechanisms and receptor interactions.
• Material Science Research: Investigated as a monomer or modifier for creating specialty polymers with unique properties.

Basic Information

Product Name	3-(Fluoromethyl)Piperidine Hcl
CAS No.	1241725-60-9
Molecular Formula	C6H13ClFN
Molecular Weight	153.63 g/mol
Synonyms	3-(Fluoromethyl)piperidine hydrochloride; Piperidine, 3-(fluoromethyl)-, hydrochloride (1:1); 3-Fluoromethylpiperidine HCl; 3-(Fluoromethyl)piperidine Hydrochloride Salt; 1241725-60-9; 3-Fluoromethyl-piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Fluoromethyl)Piperidine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.