Description

(2R,3S)-2-Phenyl-3-Pyrrolidinecarboxylic Acid CAS NO 1241680-35-2 is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined pyrrolidine core, which is a privileged scaffold for constructing biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications in asymmetric catalysis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Asymmetric Synthesis: Used as a ligand or catalyst precursor in stereoselective reactions to create enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for novel, chiral active ingredients in crop protection products.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tool compounds for studying biological systems.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and compound libraries.
• Fine Chemical Production: Integrated into multi-step synthesis pathways for complex, high-value specialty chemicals.

Basic Information

Product Name	(2R,3S)-2-Phenyl-3-Pyrrolidinecarboxylic Acid
CAS No.	1241680-35-2
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(2R,3S)-2-Phenylpyrrolidine-3-carboxylic acid; (2R,3S)-2-Phenyl-3-pyrrolidinecarboxylic acid; (2R,3S)-2-Phenyl-3-carboxypyrrolidine; 3-Pyrrolidinecarboxylic acid, 2-phenyl-, (2R,3S)-; (2R,3S)-2-Phenyl-3-pyrrolidine carboxylic acid; (2R,3S)-2-Phenyl-3-pyrrolidinecarboxylate; (2R,3S)-2-Phenyl-3-pyrrolidinecarboxylic acid hydrochloride (salt form); (2R,3S)-2-Phenyl-3-pyrrolidinecarboxylic acid methyl ester (derivative)
EINECS	Contact for details

Quality Control

Our (2R,3S)-2-Phenyl-3-Pyrrolidinecarboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.