Description

8-(Aminomethyl)-1,4-Dioxaspiro[4.5]Decan-8-Ol Hydrochloride (Wx102400) is a high-purity, protected amino alcohol building block used in advanced organic synthesis. This compound is valued for its unique spirocyclic structure, which provides a rigid scaffold and introduces both amino and hydroxyl functionalities, making it a versatile intermediate for constructing complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and fine chemical production.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Ligand and Catalyst Synthesis: Used to prepare sophisticated chiral ligands and organocatalysts for asymmetric synthesis, enhancing stereoselectivity in critical bond-forming reactions.
• Peptidomimetic Chemistry: The spirocyclic core serves as a conformationally restricted scaffold for designing and synthesizing peptidomimetics and protease inhibitors.
• Agrochemical Research: Employed as a precursor in the development of new herbicides, fungicides, and plant growth regulators with improved efficacy.
• Material Science Monomer: Can be utilized to synthesize specialized polymers and dendrimers with tailored properties for advanced material applications.
• Chemical Biology Probe Development: Acts as a versatile handle for introducing amino functionality into fluorescent probes, bioconjugation linkers, and other molecular tools.

Basic Information

Product Name	8-(Aminomethyl)-1,4-Dioxaspiro[4.5]Decan-8-Ol Hydrochloride (Wx102400)
CAS No.	1240527-50-7
Molecular Formula	C10H20ClNO3
Molecular Weight	237.73 g/mol
Synonyms	8-(Aminomethyl)-1,4-dioxaspiro[4.5]decan-8-ol hydrochloride; 1,4-Dioxaspiro[4.5]decan-8-ol, 8-(aminomethyl)-, hydrochloride; 8-(Aminomethyl)-8-hydroxy-1,4-dioxaspiro[4.5]decane hydrochloride; WX-102400; Wx102400; Protected 1-Amino-1-hydroxymethylcyclohexane hydrochloride; Acetal-protected amino diol hydrochloride.
EINECS	Contact for details

Quality Control

Our 8-(Aminomethyl)-1,4-Dioxaspiro[4.5]Decan-8-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity building blocks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.