Description

3-[4-Fluoro-3-(Trifluoromethoxy)Phenyl]Propionic Acid, 97% is a high-purity fluorinated aromatic propionic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, makes it invaluable for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate sophisticated fluorinated motifs into novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorinated phenyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its ability to influence molecular alignment and electronic properties.
• Advanced Polymer Modification: Employed to introduce fluorinated side chains into polymers, improving their chemical resistance, thermal stability, and surface properties for specialty coatings and high-performance materials.
• Chemical Biology & Proteomics: Useful as a tagging or linking agent in probe development for studying protein function and interaction, leveraging its distinct spectroscopic signature.

Basic Information

Product Name	3-[4-Fluoro-3-(Trifluoromethoxy)Phenyl]Propionic Acid, 97%
CAS No.	1240256-80-7
Molecular Formula	C10H8F4O3
Molecular Weight	252.16 g/mol
Synonyms	4-Fluoro-3-(trifluoromethoxy)hydrocinnamic acid; 3-(4-Fluoro-3-(trifluoromethoxy)phenyl)propanoic acid; 3-(4-Fluoro-3-trifluoromethoxyphenyl)propionic acid; 1240256-80-7; F-TFMOPA; 3-(4-Fluoro-3-(trifluoromethoxy)phenyl)propionic acid; 4'-Fluoro-3'-(trifluoromethoxy)phenylpropionic acid
EINECS	Contact for details

Quality Control

Every batch of 3-[4-Fluoro-3-(Trifluoromethoxy)Phenyl]Propionic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard 97% purity grade is verified by chromatographic methods (HPLC, GC) and spectroscopic analysis (NMR, IR). A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.