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5-Bromo-7-(Trifluoromethyl)Quinoline CAS NO 1239462-77-1
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CAS No.:1239462-77-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-Bromo-7-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for advanced research and development, particularly in the synthesis of complex molecules where its unique halogenated and fluorinated structure imparts critical electronic and steric properties. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials research sectors for creating novel active ingredients and functional materials.
Application
- Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
- Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
- Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and other electronic materials due to its electron-deficient quinoline core.
- Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) as a versatile halogenated substrate for constructing complex molecular architectures.
- Fluorine Chemistry Studies: An important compound for investigating the effects of fluorine substitution on the reactivity and physical properties of heterocyclic systems.
Basic Information
| Product Name | 5-Bromo-7-(Trifluoromethyl)Quinoline |
| CAS No. | 1239462-77-1 |
| Molecular Formula | C10H5BrF3N |
| Molecular Weight | 276.06 g/mol |
| Synonyms | 7-(Trifluoromethyl)-5-bromoquinoline; 5-Bromo-7-trifluoromethylquinoline; Quinoline, 5-bromo-7-(trifluoromethyl)-; 5-Bromo-7-(trifluoromethyl)chinolin; 5-Bromo-7-(trifluoromethyl)quinoleine |
| EINECS | Contact for details |
Quality Control
Our 5-Bromo-7-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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