Description

7-Bromo-5-(Trifluoromethyl)Quinoline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic combination of a bromine substituent and a trifluoromethyl group on the quinoline scaffold, enabling precise molecular modifications and introducing desirable physicochemical properties. This compound is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for developing novel active ingredients, as well as by material scientists for creating specialty functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Buchwald-Hartwig aminations.
• Fluorine Chemistry Research: An important compound for studying the effects of fluorine substitution on molecular properties in medicinal and materials chemistry.
• Ligand and Catalyst Development: Utilized to synthesize complex chelating ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	7-Bromo-5-(Trifluoromethyl)Quinoline
CAS No.	1239462-76-0
Molecular Formula	C10H5BrF3N
Molecular Weight	276.06 g/mol
Synonyms	7-Bromo-5-(trifluoromethyl)quinoline; 5-(Trifluoromethyl)-7-bromoquinoline; Quinoline, 7-bromo-5-(trifluoromethyl)-; 7-Bromo-5-trifluoromethylquinoline; 7-Br-5-CF3-Quinoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.