Description

3-(Trifluoromethyl)Quinolin-5-Amine is a high-value, fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a quinoline scaffold and a trifluoromethyl group, provides exceptional properties for modulating the bioactivity and physicochemical characteristics of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced potency and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science: Serves as a precursor for functionalized organic materials, including ligands for catalysis and monomers for specialty polymers.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to the distinct properties imparted by the fluorine atoms.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-(Trifluoromethyl)Quinolin-5-Amine
CAS No.	1239462-41-9
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	5-Amino-3-(trifluoromethyl)quinoline; 3-(Trifluoromethyl)-5-quinolinamine; 5-Quinolinamine, 3-(trifluoromethyl)-; Quinolin-5-amine, 3-(trifluoromethyl)-; 3-Trifluoromethylquinolin-5-ylamine
EINECS	Contact for details

Quality Control

Every batch of 3-(Trifluoromethyl)Quinolin-5-Amine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure compliance with the highest purity standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.