Description

7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 2-Amino-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and amino acid ester structure. This compound is critical for medicinal chemistry research and development, serving as a sophisticated building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical sectors seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve pharmacokinetic properties.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component in the linker or warhead design for novel bifunctional degrader molecules.
• Agrochemical Synthesis: Employed in the research and development of new generation pesticides and herbicides requiring specific stereochemistry.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying enzyme function and biological pathways.
• Peptidomimetic Design: The amino acid ester moiety makes it valuable for constructing peptide analogs with enhanced metabolic stability.

Basic Information

Product Name	7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 2-Amino-, 1,1-Dimethylethyl Ester
CAS No.	1239319-82-4
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	tert-Butyl 2-amino-7-azaspiro[3.5]nonane-7-carboxylate; 2-Amino-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; 7-(tert-Butoxycarbonyl)-7-azaspiro[3.5]nonan-2-amine; Boc-7-azaspiro[3.5]nonan-2-amine; 2-Amino-7-Boc-7-azaspiro[3.5]nonane; 7-Azaspiro[3.5]nonane-2-amine, 7-Boc protected; 7-Boc-7-azaspiro[3.5]nonan-2-amine
EINECS	Contact for details

Quality Control

Our 7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 2-Amino-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.