Description

3-Chloro-2'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-value biphenyl carboxylic acid derivative, distinguished by its chloro and trifluoromethyl substituents which impart unique electronic and steric properties. This compound is a critical advanced intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation, oncology, and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the stability and bioactivity of the biphenyl core.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals, where its aromatic structure and halogenated groups modify material properties.
• Organic Synthesis & Catalysis: Employed as a ligand precursor or a sophisticated scaffold in metal-catalyzed cross-coupling reactions and other advanced synthetic methodologies.

Basic Information

Product Name	3-Chloro-2'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1237080-49-7
Molecular Formula	C14H8ClF3O2
Molecular Weight	300.66 g/mol
Synonyms	[1,1'-Biphenyl]-4-carboxylic acid, 3-chloro-2'-(trifluoromethyl)-; 3-Chloro-2'-(trifluoromethyl)biphenyl-4-carboxylic acid; 4'-Chloro-3'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxylic acid; 3-Chloro-2'-trifluoromethylbiphenyl-4-carboxylic Acid; 3-Chloro-2'-(trifluoromethyl)-1,1'-biphenyl-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. All materials are fully characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.