Description

4-(Azetidin-3-Yl)Pyridine Dihydrochloride is a high-purity, heterocyclic organic building block featuring a fused pyridine-azetidine core. This compound is of significant value in medicinal chemistry and pharmaceutical research as a key intermediate for the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic programs.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Development: Serves as a precursor in the research and development of new active ingredients for crop protection.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring a specific, functionalized azetidine moiety.
• Academic Research: Used in university and institutional labs for methodological development in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	4-(Azetidin-3-Yl)Pyridine Dihydrochloride
CAS No.	1236791-32-4
Molecular Formula	C8H11N2Cl2
Molecular Weight	206.10 g/mol
Synonyms	4-(Azetidin-3-yl)pyridine dihydrochloride; 3-Pyridin-4-ylazetidine dihydrochloride; Azetidine, 3-(4-pyridinyl)-, dihydrochloride; 4-(3-Azetidinyl)pyridine dihydrochloride; Pyridine, 4-(3-azetidinyl)-, dihydrochloride; 4-Azetidin-3-ylpyridine dihydrochloride; 3-(4-Pyridyl)azetidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Azetidin-3-Yl)Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.