Description

5-Hydroxy-1-Oxo-n-[4-(Trifluoromethoxy)Phenyl]-2,3-Dihydropyrrolo[1,2-A]Quinazoline-3A(1H)-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound matters for its role as a key synthetic building block in the creation of novel therapeutic agents, particularly within specialized chemical libraries. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on medicinal chemistry and the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic molecules.
• Chemical Library Synthesis: A valuable component for constructing diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• API Development: Employed in the research-scale development and process chemistry for potential new active pharmaceutical ingredients.
• Biochemical Research: May be utilized as a tool compound or probe in biochemical assays to study specific biological interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	5-Hydroxy-1-Oxo-n-[4-(Trifluoromethoxy)Phenyl]-2,3-Dihydropyrrolo[1,2-A]Quinazoline-3A(1H)-Carboxamide
CAS No.	1236260-77-7
Molecular Formula	C20H14F3N3O4
Molecular Weight	417.34 g/mol
Synonyms	5-Hydroxy-1-oxo-N-[4-(trifluoromethoxy)phenyl]-2,3-dihydro-1H-pyrrolo[1,2-a]quinazoline-3a-carboxamide; 1H-Pyrrolo[1,2-a]quinazoline-3a-carboxamide, 2,3-dihydro-5-hydroxy-1-oxo-N-[4-(trifluoromethoxy)phenyl]-; 1236260-77-7; 5-Hydroxy-1-oxo-N-(4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-pyrrolo[1,2-a]quinazoline-3a-carboxamide; N-[4-(Trifluoromethoxy)phenyl]-5-hydroxy-1-oxo-2,3-dihydro-1H-pyrrolo[1,2-a]quinazoline-3a-carboxamide
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-1-Oxo-n-[4-(Trifluoromethoxy)Phenyl]-2,3-Dihydropyrrolo[1,2-A]Quinazoline-3A(1H)-Carboxamide is manufactured under strict quality management systems. The product undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for pharmaceutical R&D applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.