Description

8-Cyano-8-Phenyl-1-Thia-4-Azaspiro[4.5]Decane-3-Carboxylic Acid is a sophisticated spirocyclic organic compound featuring a unique heterocyclic scaffold that combines thia and aza functionalities. This structure makes it a valuable and versatile advanced pharmaceutical intermediate for the synthesis of novel active ingredients. It is primarily sought after by research organizations and fine chemical manufacturers engaged in drug discovery, particularly in developing candidates for central nervous system and metabolic disorders.

Application

• Key Intermediate in Drug Discovery: Serves as a critical building block for synthesizing novel spirocyclic compounds with potential pharmacological activity.
• Pharmaceutical Research & Development: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) and optimize lead compounds.
• Synthesis of Biologically Active Molecules: The core spiro[4.5]decane structure is leveraged to create molecules targeting specific enzymes or receptors.
• Fine Chemical Production: Employed in multi-step synthetic routes for the manufacture of high-value, complex organic molecules.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	8-Cyano-8-Phenyl-1-Thia-4-Azaspiro[4.5]Decane-3-Carboxylic Acid
CAS No.	1236255-46-1
Molecular Formula	C16H16N2O2S
Molecular Weight	300.38 g/mol
Synonyms	8-Cyano-8-phenyl-1-thia-4-azaspiro[4.5]decane-3-carboxylic acid; 1-Thia-4-azaspiro[4.5]decane-3-carboxylic acid, 8-cyano-8-phenyl-; 8-Phenyl-8-cyano-1-thia-4-azaspiro[4.5]decane-3-carboxylic acid; Spiro[4.5]decane-3-carboxylic acid derivative; CAS 1236255-46-1
EINECS	Contact for details

Quality Control

Our production of 8-Cyano-8-Phenyl-1-Thia-4-Azaspiro[4.5]Decane-3-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.