Description

6-Bromo-7-Fluoro-1,2,3,4-Tetrahydroquinoline is a high-purity, multi-functional halogenated heterocyclic building block essential for advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel pharmaceuticals and agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromine and fluorine substitutions into quinoline-based structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets where the bromo-fluoro substitution pattern is pharmacologically relevant.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated quinolines.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its electronic properties can be tuned.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of biological systems and protein interactions.
• Ligand Synthesis: Utilized for creating novel ligands in catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry and method development.

Basic Information

Item	Detail
Product Name	6-Bromo-7-Fluoro-1,2,3,4-Tetrahydroquinoline
CAS No.	1235440-09-1
Molecular Formula	C9H9BrFN
Molecular Weight	230.08 g/mol
Synonyms	6-Bromo-7-fluoro-1,2,3,4-tetrahydroquinoline; 7-Fluoro-6-bromo-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-6-bromo-7-fluoroquinoline; 6-Bromo-7-fluoro-3,4-dihydro-2H-quinoline; 6-Bromo-7-fluoro-1,2,3,4-tetrahydro-quinoline; Tetrahydroquinoline, 6-bromo-7-fluoro-; 6-Br-7-F-THQ
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-Fluoro-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.