Description

4-Amino-7,8-Dimethylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both amino and ester functional groups on the quinoline core, makes it an invaluable intermediate for the development of complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive quinoline scaffold.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for synthesizing electron-transport or emissive layer materials in display and lighting technologies.
• Coordination Chemistry & Catalysis: Acts as a versatile ligand for metal complexes used in homogeneous catalysis and material science.
• Fluorescent Probe Synthesis: Utilized to create sensitive molecular probes for bioimaging and diagnostic applications.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	4-Amino-7,8-Dimethylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1235377-71-5
Molecular Formula	C₁₄H₁₆N₂O₂
Molecular Weight	244.29 g/mol
Synonyms	Ethyl 4-Amino-7,8-dimethylquinoline-3-carboxylate; 4-Amino-7,8-dimethyl-3-quinolinecarboxylic Acid Ethyl Ester; 7,8-Dimethyl-4-aminoquinoline-3-carboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 4-amino-7,8-dimethyl-, ethyl ester; 4-Amino-7,8-dimethylquinoline-3-ethyl carboxylate
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-7,8-Dimethylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.