Description

trans-N1,N1-Dimethylcyclohexane-1,2-Diamine-2Hcl is a high-purity, chiral diamine hydrochloride salt used as a sophisticated building block and ligand in advanced chemical synthesis. Its rigid cyclohexane backbone and specific stereochemistry make it a valuable precursor for creating complex molecular architectures with defined spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel active ingredients, catalysts, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Asymmetric Catalysis Ligand: Serves as a precursor for chiral ligands used in asymmetric hydrogenation and other enantioselective transformations critical for producing single-isomer compounds.
• Complexing Agent: Used in the preparation of metal-organic frameworks (MOFs) and coordination complexes for catalysis and material science applications.
• Polymer Chemistry: Acts as a monomer or chain extender in the synthesis of specialty polyamides, polyurethanes, and epoxy curing agents with enhanced thermal and mechanical properties.
• Agrochemical Synthesis: Employed in the research and development of advanced herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Research & Development: A valuable tool for academic and industrial R&D in organic chemistry, medicinal chemistry, and process development.

Basic Information

Product Name	trans-N1,N1-Dimethylcyclohexane-1,2-Diamine-2Hcl
CAS No.	1234860-01-5
Molecular Formula	C8H20Cl2N2
Molecular Weight	215.16 g/mol
Synonyms	(1R,2R)-N1,N1-Dimethylcyclohexane-1,2-diamine dihydrochloride; (1R,2R)-N,N-Dimethyl-1,2-cyclohexanediamine dihydrochloride; trans-N,N-Dimethyl-1,2-cyclohexanediamine dihydrochloride; (R,R)-N,N-Dimethyl-1,2-diaminocyclohexane dihydrochloride; (1R,2R)-(-)-N,N-Dimethyl-1,2-cyclohexanediamine dihydrochloride; (R,R)-DACH-Diamine derivative HCl salt; trans-1,2-Diaminocyclohexane-N,N-dimethyl dihydrochloride
EINECS	Contact for details

Quality Control

Our trans-N1,N1-Dimethylcyclohexane-1,2-Diamine-2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.