Description

4-Chloro-7-Fluor-1,8-Naphthyridine-3-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Used as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Fundamental research tool in heterocyclic and medicinal chemistry for exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	4-Chloro-7-Fluor-1,8-Naphthyridine-3-Carbonitrile
CAS No.	1234616-32-0
Molecular Formula	C9H3ClFN3
Molecular Weight	207.59 g/mol
Synonyms	4-Chloro-7-fluoro-1,8-naphthyridine-3-carbonitrile; 4-Chloro-7-fluoro-1,8-naphthyridine-3-carbonitrile; 7-Fluoro-4-chloro-1,8-naphthyridine-3-carbonitrile; 3-Cyano-4-chloro-7-fluoro-1,8-naphthyridine; 1,8-Naphthyridine-3-carbonitrile, 4-chloro-7-fluoro-; 4-Chloro-7-fluoro-[1,8]naphthyridine-3-carbonitrile; 1234616-32-0
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Fluor-1,8-Naphthyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.