Description

3-Bromo-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated fused heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor for creating novel compounds with potential herbicidal or pesticidal activity.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to create diverse chemical libraries.

Basic Information

Product Name	3-Bromo-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid
CAS No.	1234616-00-2
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	3-Bromo-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; 3-Bromo-5-carboxy-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 3-bromo-; 3-Bromo-1H-7-azaindole-5-carboxylic acid; 3-Bromo-5-azaindole-5-carboxylic acid; 3-Bromo-1H-pyrrolo[2,3-b]pyridine-5-carboxylate; 3-Bromo-7-azaindole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.