Description

Di-tert-Butyl 1-(5-Pyrimidinyl)-1,2-Hydrazinedicarboxylate is a high-purity, specialized organic compound featuring a pyrimidine core protected by tert-butyloxycarbonyl (Boc) groups. This compound matters as a critical building block and protected intermediate in the synthesis of complex pharmaceuticals and advanced agrochemicals, enabling precise molecular construction. It is primarily needed by research institutions and industrial manufacturers engaged in developing active pharmaceutical ingredients (APIs), nucleoside analogs, and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key protected synthon for the development of novel antiviral and anticancer agents, particularly those containing pyrimidine scaffolds.
• Agrochemical Research: Used in the synthesis of advanced herbicides and fungicides that target specific biological pathways in plants.
• Chemical Biology & Proteomics: Serves as a reagent for modifying peptides and proteins, or in the synthesis of activity-based probes.
• Organic Synthesis: Employed as a versatile building block for constructing complex heterocyclic systems and functionalized hydrazine derivatives in medicinal chemistry.
• Material Science Precursor: Potential use in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its nitrogen-rich structure.

Basic Information

Product Name	Di-tert-Butyl 1-(5-Pyrimidinyl)-1,2-Hydrazinedicarboxylate
CAS No.	1234615-84-9
Molecular Formula	C14H22N4O4
Molecular Weight	310.35 g/mol
Synonyms	1,2-Bis(tert-butoxycarbonyl)-1-(pyrimidin-5-yl)hydrazine; 5-Pyrimidinyl-1,2-bis(tert-butoxycarbonyl)hydrazine; Di-tert-butyl (pyrimidin-5-yl)hydrazine-1,2-dicarboxylate; 1-(Pyrimidin-5-yl)hydrazine-1,2-dicarboxylic acid di-tert-butyl ester; Boc-NH-N(Boc)-Pyrimidin-5-yl; 5-(1,2-Bis(tert-butoxycarbonyl)hydrazinyl)pyrimidine
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl 1-(5-Pyrimidinyl)-1,2-Hydrazinedicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.