Description

(1R*,4R*)-4-(2-Aminophenylamino)Cyclohexanol CAS NO 1233955-54-8 is a high-purity chiral amine derivative featuring both cyclohexanol and phenylenediamine moieties. This compound matters as a sophisticated pharmaceutical intermediate and chiral building block for the synthesis of complex active molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Building block for advanced pesticides and herbicides requiring specific stereochemistry for efficacy.
• Ligand & Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis in fine chemical manufacturing.
• Research & Development: Critical material for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Dye & Pigment Chemistry: Intermediate in the production of specialized, high-performance colorants.
• Polymer Modification: Functional monomer for creating specialty polymers with amine and hydroxyl reactivity.

Basic Information

Product Name	(1R*,4R*)-4-(2-Aminophenylamino)Cyclohexanol
CAS No.	1233955-54-8
Molecular Formula	C12H18N2O
Molecular Weight	206.29 g/mol
Synonyms	4-[(2-Aminophenyl)amino]cyclohexanol (rel-(1R,4R)-form); (1R,4R)-4-(2-Aminoanilino)cyclohexan-1-ol; trans-4-(2-Aminophenylamino)cyclohexanol; 2-[(4-Hydroxycyclohexyl)amino]aniline; 1,4-Cyclohexanediol, 4-(2-aminophenyl)amino-, (1R,4R)-; CAS 1233955-54-8; Aminophenylaminocyclohexanol
EINECS	Contact for details

Quality Control

Our (1R*,4R*)-4-(2-Aminophenylamino)Cyclohexanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical parameters to ensure compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.