Description

2-Fluoro-n-(Piperidin-4-Yl)Benzenesulfonamide Hydrochloride is a high-purity, functionalized sulfonamide building block of significant interest in modern synthetic chemistry. Its core value lies in its dual functionality, combining a fluorinated aromatic sulfonamide group with a piperidine scaffold, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the development of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of small molecule drug candidates, especially in oncology and CNS research.
• Kinase Inhibitor Development: Used to construct pharmacophores targeting specific kinase enzymes due to the sulfonamide and piperidine motifs.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides with enhanced activity.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in client-directed synthesis projects requiring this specific scaffold.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2-Fluoro-n-(Piperidin-4-Yl)Benzenesulfonamide Hydrochloride
CAS No.	1233955-52-6
Molecular Formula	C11H16ClFN2O2S
Molecular Weight	294.77 g/mol
Synonyms	4-[(2-Fluorobenzenesulfonyl)amino]piperidine hydrochloride; 1-(2-Fluorophenyl)sulfonyl-4-piperidinamine hydrochloride; N-(Piperidin-4-yl)-2-fluorobenzenesulfonamide hydrochloride; 2-Fluoro-N-(4-piperidinyl)benzenesulfonamide HCl; 2-Fluoro-benzenesulfonic acid piperidin-4-ylamide hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-n-(Piperidin-4-Yl)Benzenesulfonamide Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.