Description

n-(3-Nitrobenzyl)Piperidine-4-Amine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those with piperidine-based pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Neurological & CNS Drug Development: Serves as a precursor for compounds targeting neurological receptors and enzymes.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.
• Academic & Institutional Research: Employed in university and government labs for fundamental organic synthesis and pharmacological studies.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) performing custom synthesis projects.

Basic Information

Product Name	n-(3-Nitrobenzyl)Piperidine-4-Amine Dihydrochloride
CAS No.	1233955-00-4
Molecular Formula	C12H18N3O2 • 2HCl
Molecular Weight	309.21 g/mol (Free base: 236.29 g/mol)
Synonyms	1-[(3-Nitrophenyl)methyl]-4-piperidinamine dihydrochloride; 4-Amino-1-(3-nitrobenzyl)piperidine dihydrochloride; N-(3-Nitrobenzyl)-4-aminopiperidine dihydrochloride; 1-(3-Nitrobenzyl)piperidin-4-amine dihydrochloride; 4-Piperidinamine, 1-[(3-nitrophenyl)methyl]-, dihydrochloride; 3-Nitrobenzyl-4-aminopiperidine dihydrochloride
EINECS	Contact for details

Quality Control

Our n-(3-Nitrobenzyl)Piperidine-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.