Description

n-(2-Fluoro-6-Nitrophenyl)Piperidin-4-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific aromatic fluorine and nitro substitution pattern. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system and oncological pathways. It is primarily required by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and biotechnology sectors engaged in innovative small-molecule drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential therapeutic agents, especially for neurological and psychiatric disorders.
• Drug Discovery Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new chemical entities with optimized biological activity.
• Process Chemistry Development: Serves as a standard reference material for scaling up and optimizing synthetic routes in pilot plants and commercial manufacturing.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and receptor interactions in biological systems.
• Agrochemical Research: Potential application as a synthetic intermediate in the development of new crop protection agents and herbicides.

Basic Information

Item	Detail
Product Name	n-(2-Fluoro-6-Nitrophenyl)Piperidin-4-Amine Hydrochloride
CAS No.	1233954-80-7
Molecular Formula	C11H15FN3O2 • HCl
Molecular Weight	273.71 g/mol (Free base) / 310.17 g/mol (Hydrochloride salt)
Synonyms	4-Amino-1-(2-fluoro-6-nitrophenyl)piperidine hydrochloride; 1-(2-Fluoro-6-nitrophenyl)piperidin-4-amine hydrochloride; 2-Fluoro-6-nitro-N-(piperidin-4-yl)aniline hydrochloride; 4-(2-Fluoro-6-nitroanilino)piperidine hydrochloride; 1233954-80-7 (CAS); n-(2-Fluoro-6-nitrophenyl)-4-piperidinamine hydrochloride
EINECS	Contact for details

Quality Control

Our n-(2-Fluoro-6-Nitrophenyl)Piperidin-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.