Description

1-(4-Fluoro-2-Nitrophenyl)Piperidin-4-Amine Hydrochloride is a high-purity, synthetically derived organic compound primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a versatile building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced material science industries seeking to create new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides that incorporate fluorinated aromatic and piperidine motifs.
• Chemical Synthesis Scaffold: Used in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its reactive amine and nitro functional groups.
• API Development: Integral in the multi-step synthesis of complex target molecules during the process research and scale-up phases of API manufacturing.
• Bioconjugation & Probe Synthesis: The amine functionality allows for conjugation to biomarkers, fluorescent tags, or other molecules for diagnostic and research applications.

Basic Information

Product Name	1-(4-Fluoro-2-Nitrophenyl)Piperidin-4-Amine Hydrochloride
CAS No.	1233952-91-4
Molecular Formula	C11H15FN3O2 • HCl
Molecular Weight	261.71 g/mol (Free base); 298.17 g/mol (Hydrochloride salt)
Synonyms	4-Amino-1-(4-fluoro-2-nitrophenyl)piperidine hydrochloride; 1-(4-Fluoro-2-nitrophenyl)-4-piperidinamine hydrochloride; 4-Piperidinamine, 1-(4-fluoro-2-nitrophenyl)-, hydrochloride; 1-(4-Fluoro-2-nitrophenyl)piperidin-4-amine HCl; 4-Amino-1-(4-fluoro-2-nitrophenyl)piperidine HCl salt; 1233952-91-4; 1-(4-Fluoro-2-nitro-phenyl)-piperidin-4-ylamine hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Each batch is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request and are provided with every shipment to ensure traceability and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.