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Bis[Di-tert-Butyl(4-Dimethylaminophenyl)Phosphine]Palladium(0) CAS NO 1233717-68-4
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CAS No.:1233717-68-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Bis[Di-tert-Butyl(4-Dimethylaminophenyl)Phosphine]Palladium(0) is a highly specialized, air-stable palladium(0) catalyst prized for its exceptional electron-richness and steric bulk. This compound matters for enabling challenging cross-coupling reactions under mild conditions with high selectivity and yield. It is essential for researchers and process chemists in pharmaceutical development, advanced material synthesis, and fine chemical manufacturing who require a reliable, high-performance catalyst for constructing complex molecular architectures.
Application
- Pharmaceutical Intermediate Synthesis: A premier catalyst for Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi cross-coupling reactions in API development.
- Advanced Material Research: Used in the synthesis of conjugated polymers, organic semiconductors, and liquid crystals for electronic applications.
- Fine Chemical Production: Facilitates the formation of carbon-heteroatom and carbon-carbon bonds in high-value specialty chemicals.
- Methodology Development: Employed in academic and industrial R&D for developing new catalytic protocols and exploring novel reaction pathways.
- Scale-up Process Chemistry: Suitable for optimizing and scaling coupling reactions from laboratory to pilot plant scale due to its stability.
- Ligand-Scope Evaluation: Serves as a benchmark catalyst for evaluating the performance of new phosphine ligands in palladium-catalyzed transformations.
Basic Information
| Product Name | Bis[Di-tert-Butyl(4-Dimethylaminophenyl)Phosphine]Palladium(0) |
| CAS No. | 1233717-68-4 |
| Molecular Formula | C36H58N2P2Pd |
| Molecular Weight | 695.21 g/mol |
| Synonyms | Bis(di-tert-butyl(4-(dimethylamino)phenyl)phosphine)palladium(0); Pd(dtbpf)₂; Palladium(0) bis[di-tert-butyl(4-dimethylaminophenyl)phosphine]; dtbpf-Pd(0) complex; Palladium(0) complex with 2-(di-tert-butylphosphino)-N,N-dimethylaniline; (4-(Dimethylamino)phenyl)di-tert-butylphosphine palladium(0) dimer; CAS 1233717-68-4 |
| EINECS | Contact for details |
Quality Control
Every batch of our Bis[Di-tert-Butyl(4-Dimethylaminophenyl)Phosphine]Palladium(0) is synthesized and handled under strict inert atmosphere conditions to ensure maximum activity and purity. We employ advanced analytical techniques, including NMR (1H, 31P) and elemental analysis, to verify identity and assay. Certificates of Analysis (COA) detailing lot-specific purity and performance data are provided to guarantee consistent quality and reliability for your critical synthetic applications.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to brown powder or crystals |
| Identification (NMR) | Conforms to structure |
| Assay (Pd content) | ≥ 14.5 % |
| Purity (HPLC) | ≥ 97.0 % |
| Solubility | Soluble in common organic solvents (THF, Toluene, DCM) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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