Description

2-Ethynyl-1-Methyl-4-Nitrobenzene is a specialized aromatic compound featuring a nitro group and an ethynyl substituent, making it a valuable building block in advanced organic synthesis. Its unique structure provides a versatile platform for constructing complex molecules, particularly in the development of pharmaceuticals and functional materials. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and advanced polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific biological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for Sonogashira coupling and other palladium-catalyzed cross-coupling reactions to create complex aromatic systems.
• Dye & Pigment Industry: Employed in the research and synthesis of novel nitro-aromatic dyes and colorants.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic routes in university and corporate research laboratories.

Basic Information

Product Name	2-Ethynyl-1-Methyl-4-Nitrobenzene
CAS No.	1233521-02-2
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	1-Methyl-2-ethynyl-4-nitrobenzene; 4-Nitro-2-ethynyltoluene; 2-Methyl-5-nitrobenzeneacetylene; 2-Ethynyl-4-nitrotoluene; 2-Methyl-5-nitrophenylacetylene; (2-Methyl-5-nitrophenyl)ethyne
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-1-Methyl-4-Nitrobenzene is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.