Description

4-(n-Boc-Aminophenyl)Acetonitrile is a protected aniline derivative of significant value as a versatile synthetic intermediate in organic chemistry. This compound is crucial for the controlled introduction of an amino group into complex molecular architectures, enabling the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing aniline or benzylamine pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where its protected amine functionality allows for selective reactions.
• Peptide Mimetics & Linkers: Serves as a precursor for constructing non-natural amino acids and specialized linkers used in peptide-based drug discovery and bioconjugation.
• Material Science Research: Employed in the development of organic semiconductors, dyes, and polymers where its aromatic nitrile and protected amine groups contribute to desired electronic or structural properties.
• Chemical Biology Probes: Utilized as a starting material for creating fluorescent tags, affinity labels, and other molecular probes for biological research.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	4-(n-Boc-Aminophenyl)Acetonitrile
CAS No.	1233249-35-8
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.31 g/mol
Synonyms	4-(tert-Butoxycarbonylamino)phenylacetonitrile; 4-(Boc-amino)phenylacetonitrile; 2-[4-[(tert-Butoxycarbonyl)amino]phenyl]acetonitrile; 4-(Boc-Amino)benzyl cyanide; N-Boc-4-cyanobenzylamine; tert-Butyl [4-(cyanomethyl)phenyl]carbamate; p-(Boc-Amino)phenylacetonitrile
EINECS	Contact for details

Quality Control

Our 4-(n-Boc-Aminophenyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.