Description

4-Bromo-2-Hydrazinylbenzoic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. Its unique structure, featuring both a bromo substituent and a hydrazinyl group, makes it a critical precursor for synthesizing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is essential for research and production in pharmaceutical chemistry, agrochemical development, and advanced material science, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators that require specific halogenated benzoic acid derivatives.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocycles like indazoles, benzimidazoles, and cinnolines through cyclization and coupling reactions.
• Chemical Research & Development: A valuable tool in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) and functional polymers.

Basic Information

Product Name	4-Bromo-2-Hydrazinylbenzoic Acid Hydrochloride
CAS No.	1231892-17-3
Molecular Formula	C7H8BrN2O2 • HCl
Molecular Weight	267.52 g/mol (Free base: 231.06 g/mol)
Synonyms	2-Hydrazinyl-4-bromobenzoic acid hydrochloride; 4-Bromo-2-hydrozinylbenzoic acid HCl; Benzoic acid, 4-bromo-2-hydrazinyl-, hydrochloride; 4-Bromo-2-hydrazinobenzoic acid hydrochloride; 2-Amino-4-bromobenzoic acid hydrazide hydrochloride (tautomeric form); 4-Bromoanthranilic acid hydrazide hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Hydrazinylbenzoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.