Description

(1-(2-Fluorophenyl)Cyclobutyl)Methanamine Hydrochloride is a high-purity, synthetically derived organic compound, specifically a fluorinated cyclobutylamine hydrochloride salt. This compound is a crucial pharmaceutical intermediate and building block in modern medicinal chemistry, valued for its unique structural motif that can impart specific biological activity and metabolic stability to drug candidates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Its structural features make it relevant for researching potential treatments for neurological and psychiatric disorders.
• Oncological Research: Used in the synthesis of targeted small-molecule inhibitors for cancer therapy.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production of clinical trial materials.

Basic Information

Product Name	(1-(2-Fluorophenyl)Cyclobutyl)Methanamine Hydrochloride
CAS No.	1228879-43-3
Molecular Formula	C11H15ClFN
Molecular Weight	215.69 g/mol
Synonyms	1-(2-Fluorophenyl)cyclobutanemethanamine hydrochloride; 2-Fluoro-α-(cyclobutylmethyl)benzylamine hydrochloride; (1-(2-Fluorophenyl)cyclobutyl)methanamine HCl; 1-(2-Fluorophenyl)cyclobutylmethylamine hydrochloride; α-(Cyclobutylmethyl)-2-fluorobenzylamine hydrochloride; (1-(o-Fluorophenyl)cyclobutyl)methanamine hydrochloride; 2-Fluoro-α-(cyclobutylmethyl)benzenemethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1-(2-Fluorophenyl)Cyclobutyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR, IR, and MS. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment supports applications requiring high standards of chemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.