Description

Cyclobutanemethanamine, 1-(2-Bromophenyl)-, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate with a unique bridged-ring structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates targeting neurological disorders.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists exploring structure-activity relationships (SAR) in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production of complex APIs, especially those containing functionalized cyclobutane and aromatic bromine motifs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	Cyclobutanemethanamine, 1-(2-Bromophenyl)-, Hydrochloride (1:1)
CAS No.	1228879-39-7
Molecular Formula	C11H14BrN•HCl
Molecular Weight	276.60 g/mol
Synonyms	1-(2-Bromophenyl)cyclobutanemethanamine Hydrochloride; 1-(2-Bromophenyl)-1-cyclobutanemethylamine Hydrochloride; 1-(2-Bromophenyl)cyclobutylmethylamine HCl; (1-(2-Bromophenyl)cyclobutyl)methanamine Hydrochloride; 1-(2-Bromophenyl)cyclobutan-1-ylmethanamine Hydrochloride; α-(2-Bromophenyl)-α-cyclobutanemethylamine Hydrochloride; 2-Bromo-α-(cyclobutylmethyl)benzylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our Cyclobutanemethanamine, 1-(2-Bromophenyl)-, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material suitable for research use and can supply under cGMP guidelines for advanced clinical phases upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.