Description

[1-(4-Fluorophenyl)Cyclobutyl]Methanamine, Hcl is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its unique structural motif, which is crucial for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the fluorophenyl group for enhanced biological activity and stability.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for constructing complex molecular architectures in academic and industrial R&D labs.
• Ligand and Catalyst Development: Potential precursor for designing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science: Investigated for incorporation into specialty polymers and advanced organic materials requiring specific fluorinated components.

Basic Information

Product Name	[1-(4-Fluorophenyl)Cyclobutyl]Methanamine, Hcl
CAS No.	1228879-30-8
Molecular Formula	C11H15FN • HCl
Molecular Weight	201.70 g/mol (Free base: 165.24 g/mol)
Synonyms	1-(4-Fluorophenyl)cyclobutanemethanamine hydrochloride; [1-(4-Fluorophenyl)cyclobutyl]methanamine hydrochloride; 4-Fluoro-α-(cyclobutylmethyl)benzylamine hydrochloride; (1-(4-Fluorophenyl)cyclobutyl)methanamine HCl; 1-(4-Fluorophenyl)cyclobutan-1-ylmethanamine hydrochloride; 4-Fluorophenyl cyclobutyl methanamine HCl; FCBMA-HCl
EINECS	Contact for details

Quality Control

Our [1-(4-Fluorophenyl)Cyclobutyl]Methanamine, Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.