Description

2,2,2-Trifluoro-1-(4-Trifluoromethyl-Phenyl)-Ethylamine Hydrochloride is a high-purity, fluorinated aromatic amine hydrochloride salt, a key building block in advanced organic synthesis. Its value lies in the unique reactivity and stability imparted by the trifluoromethyl and trifluoroethyl groups, which are critical for modulating the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral drugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Material Science Research: Serves as a precursor for fluorinated polymers, liquid crystals, and advanced organic electronic materials due to its ability to introduce fluorine motifs.
• Chemical Biology & Proteomics: Employed as a specialty reagent for labeling and modifying biomolecules, leveraging the fluorine tag for studies using 19F NMR spectroscopy.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & R&D Laboratories: Used in discovery chemistry for exploring new synthetic methodologies and creating libraries of fluorinated compounds for screening.

Basic Information

Product Name	2,2,2-Trifluoro-1-(4-Trifluoromethyl-Phenyl)-Ethylamine Hydrochloride
CAS No.	1228879-03-5
Molecular Formula	C9H6ClF6N
Molecular Weight	277.60 g/mol
Synonyms	α,α,α-Trifluoro-4-(trifluoromethyl)phenethylamine hydrochloride; 1-[4-(Trifluoromethyl)phenyl]-2,2,2-trifluoroethylamine hydrochloride; 4-(Trifluoromethyl)-α,α,α-trifluorophenethylamine hydrochloride; 2,2,2-Trifluoro-1-[4-(trifluoromethyl)phenyl]ethanamine hydrochloride; (4-Trifluoromethylphenyl)trifluoroethylamine HCl; 1-(4-Trifluoromethylphenyl)-2,2,2-trifluoroethanamine hydrochloride; TFMP-TFEA HCl; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(4-Trifluoromethyl-Phenyl)-Ethylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.