Description

3-Iodo-1,5-Naphthyridine is a high-value halogenated heterocyclic building block, specifically engineered for advanced pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the introduction of iodine for further functionalization via cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as OLEDs and semiconductors.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings.
• Ligand and Catalyst Development: Used to synthesize novel nitrogen-containing ligands for metal complexes.
• Chemical Biology Probes: Employed in the creation of tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	3-Iodo-1,5-Naphthyridine
CAS No.	1228666-28-1
Molecular Formula	C8H5IN2
Molecular Weight	256.04 g/mol
Synonyms	1,5-Naphthyridine, 3-iodo-; 3-Iodo-1,5-naphthyridine; 3-Iodo[1,5]naphthyridine; 3-Iodo-1,5-diazanaphthalene; 1228666-28-1; 3-Iodo-1,5-naphthyridine (CAS 1228666-28-1); 3-Iodo-1,5-naphthyridine, 95+%
EINECS	Contact for details

Quality Control

Our 3-Iodo-1,5-Naphthyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.