Description

6-Fluoro-3,4-Dihydro-2H-Pyrano[2,3-B]Pyridine is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorine atoms and fused pyranopyridine scaffolds into their target molecules. The CAS number for this compound is 1228666-24-7.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorinated pyranopyridine core can enhance biological activity and environmental stability.
• Material Science Precursor: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological studies and the exploration of new synthetic routes involving fluorinated heterocycles.
• Custom Synthesis: A starting point for the bespoke synthesis of complex, fluorinated fine chemicals for specialized industrial applications.

Basic Information

Product Name	6-Fluoro-3,4-Dihydro-2H-Pyrano[2,3-B]Pyridine
CAS No.	1228666-24-7
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	6-Fluoro-3,4-dihydro-2H-pyrano[2,3-b]pyridine; 2H-Pyrano[2,3-b]pyridine, 6-fluoro-3,4-dihydro-; 6-Fluoro-2H,3H,4H-pyrano[2,3-b]pyridine; 6-Fluoropyrano[2,3-b]pyridine; 1228666-24-7; FC-2345 (Potential Research Code); Fluorinated Pyranopyridine Intermediate
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3,4-Dihydro-2H-Pyrano[2,3-B]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.