Description

(S)-4-Bromo-2,3-Dihydro-1H-Inden-1-Amine-Hcl CAS NO 1228570-71-5 is a high-purity chiral amine hydrochloride salt, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, which is essential for developing compounds with specific biological activity. This product is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity in industrial chemical processes.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Institutional Research: Employed in methodological studies and the discovery of new chemical entities (NCEs) within university and contract research organization (CRO) settings.
• Material Science: Potential precursor for chiral dopants in liquid crystal displays (LCDs) or other advanced functional materials requiring specific stereochemistry.

Basic Information

Product Name	(S)-4-Bromo-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride
CAS No.	1228570-71-5
Molecular Formula	C9H11BrClN
Molecular Weight	248.55 g/mol
Synonyms	(1S)-4-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride; (S)-4-Bromoindan-1-amine hydrochloride; (S)-1-Amino-4-bromoindane hydrochloride; 4-Bromo-(1S)-indan-1-amine hydrochloride; (S)-4-Bromo-1-indanamine hydrochloride; (1S)-4-Bromo-2,3-dihydro-1H-inden-1-amine HCl; 1228570-71-5; (S)-4-Br-indan-1-amine HCl
EINECS	Contact for details

Quality Control

Our (S)-4-Bromo-2,3-Dihydro-1H-Inden-1-Amine-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing batch-specific results is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.