Description

(S)-2-(1-Aminoethyl)-4-Chlorophenol is a chiral organic compound featuring both a phenolic hydroxyl group and a primary amine on a stereogenic center. This unique bifunctional structure makes it a valuable chiral building block and key intermediate in sophisticated organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutics.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators for enhanced efficacy.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Synthesis: Employed in creating chiral monomers for specialty polymers and liquid crystals.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme mechanisms and receptor interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high optical purity.

Basic Information

Product Name	(S)-2-(1-Aminoethyl)-4-Chlorophenol
CAS No.	1228569-39-8
Molecular Formula	C8H10ClNO
Molecular Weight	171.62 g/mol
Synonyms	(S)-1-(5-Chloro-2-hydroxyphenyl)ethan-1-amine; (S)-1-(5-Chloro-2-hydroxyphenyl)ethylamine; (S)-α-Methyl-5-chlorosalicylamine; (S)-2-Amino-1-(5-chloro-2-hydroxyphenyl)ethane; (S)-4-Chloro-2-(1-aminoethyl)phenol; (1S)-1-(5-Chloro-2-hydroxyphenyl)ethanamine
EINECS	Contact for details

Quality Control

Every batch of (S)-2-(1-Aminoethyl)-4-Chlorophenol is produced and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.