Description

2-((1S)-1-Aminoethyl)-5-Methoxyphenol CAS NO 1228553-89-6 is a chiral, substituted phenol derivative featuring both an aminoethyl and a methoxy functional group, making it a versatile and valuable chiral building block. This compound is of significant interest for its potential role in the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Fine Chemical Building Block: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical purity.
• Biochemical Research: Utilized in academic and industrial research to study enzyme interactions and develop biochemical probes.
• Material Science: Potential monomer or modifier for creating specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	2-((1S)-1-Aminoethyl)-5-Methoxyphenol
CAS No.	1228553-89-6
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(S)-1-(3-Hydroxy-4-methoxyphenyl)ethylamine; (1S)-1-(3-Hydroxy-4-methoxyphenyl)ethanamine; 5-Methoxy-2-[(1S)-1-aminoethyl]phenol; L-2-(1-Aminoethyl)-5-methoxyphenol; (S)-2-(1-Aminoethyl)-5-methoxyphenol; 4-Methoxy-3-[(1S)-1-aminoethyl]phenol
EINECS	Contact for details

Quality Control

Our 2-((1S)-1-Aminoethyl)-5-Methoxyphenol is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.