Description

(3R)-3-Amino-3-(2,5-Dimethoxyphenyl)Propanoic Acid CAS NO 1228543-14-3 is a chiral, non-proteinogenic amino acid derivative featuring a dimethoxyphenyl substituent. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its structural complexity and stereochemical purity. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), especially in areas targeting central nervous system (CNS) disorders and other therapeutic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block for constructing complex, stereochemically defined molecules in medicinal chemistry.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and mimetics due to its non-natural amino acid backbone.
• Chemical Biology Probes: Utilized in the development of molecular probes and tools for studying biological pathways and enzyme functions.
• Catalyst and Ligand Development: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Academic & Industrial R&D: A valuable compound for research institutions and chemical companies exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	(3R)-3-Amino-3-(2,5-Dimethoxyphenyl)Propanoic Acid
CAS No.	1228543-14-3
Molecular Formula	C11H15NO4
Molecular Weight	225.24 g/mol
Synonyms	(R)-3-Amino-3-(2,5-dimethoxyphenyl)propanoic acid; β-Amino-2,5-dimethoxybenzenepropanoic acid, (3R)-; (3R)-3-Amino-3-(2,5-dimethoxyphenyl)propionic acid; (R)-3-Amino-3-(2,5-dimethoxyphenyl)propionic acid; (R)-2,5-Dimethoxy-β-phenyl-β-alanine; (3R)-Amino-(2,5-dimethoxyphenyl)propanoic Acid; D-2,5-Dimethoxyphenyl-β-alanine (non-standard); 1228543-14-3
EINECS	Contact for details

Quality Control

Our (3R)-3-Amino-3-(2,5-Dimethoxyphenyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets high-purity standards suitable for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.