Description

(2S)-2-(4-Bromo-2-Fluorophenyl)Pyrrolidine is a high-purity chiral pyrrolidine derivative, a crucial building block in modern pharmaceutical and agrochemical synthesis. Its value lies in its unique stereochemistry and halogenated aromatic structure, enabling the construction of complex molecules with specific biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical industry for the development of new active pharmaceutical ingredients (APIs), particularly in areas like central nervous system (CNS) therapeutics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for neurological and psychiatric disorders.
• Agrochemical Synthesis: Used as a precursor in creating advanced pesticides and herbicides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a scaffold for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed in probe and tool compound development for studying biological pathways and target validation.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	(2S)-2-(4-Bromo-2-Fluorophenyl)Pyrrolidine
CAS No.	1228542-45-7
Molecular Formula	C10H11BrFN
Molecular Weight	244.11 g/mol
Synonyms	(S)-2-(4-Bromo-2-fluorophenyl)pyrrolidine; (2S)-2-(4-Bromo-2-fluorophenyl)-1-pyrrolidine; 4-Bromo-2-fluoro-α-[(2S)-2-pyrrolidinyl]benzene; (S)-4-Bromo-2-fluoro-α-(2-pyrrolidinyl)benzene; (S)-2-(4-Bromo-2-fluorophenyl)pyrrolidine; Pyrrolidine, 2-(4-bromo-2-fluorophenyl)-, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-2-(4-Bromo-2-Fluorophenyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.