Description

1-(2-(Trifluoromethyl)Pyridin-4-Yl)Hydrazine is a high-purity, specialized heterocyclic building block featuring a hydrazine moiety attached to a trifluoromethyl-substituted pyridine ring. This compound is valued for its unique reactivity profile, enabling the synthesis of complex molecules with enhanced physicochemical properties. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for constructing molecular probes and bioconjugation reagents due to the reactive hydrazine handle.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(2-(Trifluoromethyl)Pyridin-4-Yl)Hydrazine
CAS No.	1228535-68-9
Molecular Formula	C6H6F3N3
Molecular Weight	177.13 g/mol
Synonyms	4-Hydrazinyl-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)pyridine-4-hydrazine; 1-[2-(Trifluoromethyl)-4-pyridinyl]hydrazine; 1-(2-Trifluoromethylpyridin-4-yl)hydrazine; 4-Hydrazino-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-4-pyridylhydrazine; 1-(2-(Trifluoromethyl)pyridin-4-yl)hydrazine
EINECS	Contact for details

Quality Control

Our 1-(2-(Trifluoromethyl)Pyridin-4-Yl)Hydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.