Description

Spiro[2.5]Octan-5-Amine is a specialized spirocyclic amine building block of significant interest in advanced organic synthesis. Its unique, rigid three-dimensional structure makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new generation herbicides and fungicides with unique modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic frameworks with specific structural properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	Spiro[2.5]Octan-5-Amine
CAS No.	1228531-38-1
Molecular Formula	C8H15N
Molecular Weight	125.21 g/mol
Synonyms	5-Aminospiro[2.5]octane; Spiro[2.5]octan-5-amine; 5-Azaspiro[2.5]octane (incorrect but common misnomer); 1-Azaspiro[2.5]octan-5-amine; 5-Amino-1-azaspiro[2.5]octane; 5-Aminospirooctane; Bicyclo[3.1.0]hexane-1-carboxamine, hexahydro-
EINECS	Contact for details

Quality Control

Our Spiro[2.5]Octan-5-Amine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.